Propecia

Ingredient Name: FINASTERIDE (fi-NAS-teer-ide)



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Drug Manufacturer: MERCK, SHARP & DOHME

Common Uses: Propecia - Finasteride is an androgen hormone inhibitor used to treat male pattern hair loss IN MEN ONLY.

At 12 months, 58% of men in the placebo group had further hair loss (defined as any decrease in hair count from baseline), compared with 14% of men treated with PROPECIA. In men treated for up to 2 years, 72% of men in the placebo group demonstrated hair loss, compared with 17% of men treated with PROPECIA. At 5 years, 100% of men in the placebo group demonstrated hair loss, compared with 35% of men treated with PROPECIA.

Before Using Propecia - Finasteride: Some medicines or medical conditions may interact with Propecia - Finasteride.
INFORM YOUR DOCTOR OR PHARMACIST of all prescription and over-the-counter medicine that you are taking. Inform your doctor of any other medical conditions, allergies, or pregnancy.
USE OF Propecia - Finasteride IS NOT RECOMMENDED if you are female. Contact your doctor or pharmacist if you have any questions or concerns about using Propecia - Finasteride.

How to Use Propecia - Finasteride: Follow the directions for using Propecia - Finasteride provided by your doctor. Propecia - Finasteride COMES WITH A PATIENT INFORMATION LEAFLET. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about Propecia - Finasteride. Propecia - Finasteride may be taken on an empty stomach or with food. STORE Propecia - Finasteride at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly-closed container, away from moisture. IF YOU MISS A DOSE OF Propecia - Finasteride and you remember the same day, take it as soon as possible. If you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions: IT MAY TAKE SEVERAL MONTHS for Propecia - Finasteride to work. Do not stop taking Propecia - Finasteride without checking with your doctor. Stopping Propecia - Finasteride will result in a return within 12 months to the same amount of baldness as when you started. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are taking Propecia - Finasteride. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. ANY WOMAN WHO IS PREGNANT OR WHO MAY BECOME PREGNANT SHOULD NOT HANDLE crushed or broken tablets of Propecia - Finasteride. If a woman who is pregnant comes in contact with crushed or broken tablets of Propecia - Finasteride, contact your doctor as soon as possible.

Finasteride has no affinity for the androgen receptor and has no androgenic, antiandrogenic, estrogenic, antiestrogenic, or progestational effects. Inhibition of Type II 5a-reductase blocks the peripheral conversion of testosterone to DHT, resulting in significant decreases in serum and tissue DHT concentrations. Finasteride produces a rapid reduction in serum DHT concentration, reaching 65% suppression within 24 hours of oral dosing with a 1-mg tablet. Mean circulating levels of testosterone and estradiol were increased by approximately 15% as compared to baseline, but these remained within the physiologic range.
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